Decomposition of number of life years lost according to causes of death

被引:102
作者
Andersen, P. K. [1 ]
机构
[1] Univ Copenhagen, Dept Biostat, DK-1014 Copenhagen K, Denmark
关键词
competing risks; life expectancy; pseudo-observations; restricted mean; standard mortality rates; survival analysis; MEAN SURVIVAL-TIME; COMPETING RISKS; REGRESSION-ANALYSIS; MODELS;
D O I
10.1002/sim.5903
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
We study the competing risks model and show that the cause j cumulative incidence function integrated from 0 to has a natural interpretation as the expected number of life years lost due to cause j before time . This is analogous to the -restricted mean lifetime, which is the survival function integrated from 0 to . It is discussed how the number of years lost may be related to subject-specific explanatory variables in a regression model based on pseudo-observations, and the method is exemplified using data from a bone marrow transplantation study. Finally, inclusion of standard mortality rates is discussed. Copyright (c) 2013 John Wiley & Sons, Ltd.
引用
收藏
页码:5278 / 5285
页数:8
相关论文
共 17 条
[1]  
Andersen P. K., 1993, Statistical Models Based on Counting Processes.Springer Series in Statistics
[2]   Competing risks in epidemiology: possibilities and pitfalls [J].
Andersen, Per Kragh ;
Geskus, Ronald B. ;
de Witte, Theo ;
Putter, Hein .
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2012, 41 (03) :861-870
[3]   Interpretability and importance of functionals in competing risks and multistate models [J].
Andersen, Per Kragh ;
Keiding, Niels .
STATISTICS IN MEDICINE, 2012, 31 (11-12) :1074-1088
[4]   Regression analysis of restricted mean survival time based on pseudo-observations [J].
Andersen, PK ;
Hansen, MG ;
Klein, JP .
LIFETIME DATA ANALYSIS, 2004, 10 (04) :335-350
[5]   Generalised linear models for correlated pseudo-observations, with applications to multi-state models [J].
Andersen, PK ;
Klein, JP ;
Rosthoj, S .
BIOMETRIKA, 2003, 90 (01) :15-27
[6]   An integrated approach to cause-of-death analysis:: cause-deleted life tables and decompositions of life expectancy [J].
Beltran-Sanchez, Hiram ;
Preston, Samuel H. ;
Canudas-Romo, Vladimir .
DEMOGRAPHIC RESEARCH, 2008, 19 :1323-1350
[7]  
Binder N, LIFETIME DA IN PRESS
[8]   On pseudo-values for regression analysis in competing risks models [J].
Graw, Frederik ;
Gerds, Thomas A. ;
Schumacher, Martin .
LIFETIME DATA ANALYSIS, 2009, 15 (02) :241-255
[9]   THE STANDARD ERROR OF AN ESTIMATE OF EXPECTATION OF LIFE, WITH SPECIAL REFERENCE TO EXPECTATION OF TUMOURLESS LIFE IN EXPERIMENTS WITH MICE [J].
IRWIN, JO .
JOURNAL OF HYGIENE, 1949, 47 (02) :188-189
[10]   RESTRICTED MEAN-LIFE WITH ADJUSTMENT FOR COVARIATES [J].
KARRISON, T .
JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION, 1987, 82 (400) :1169-1176