Heterochromatin: A meiotic matchmaker?

被引：31

作者：

Renauld, H

Gasser, SM

机构：

[1] Chromatin Unit, Swiss Inst. for Exp. Cancer Research, CH-1066 Epalinges s/Lausanne

来源：

TRENDS IN CELL BIOLOGY | 1997年 / 7卷 / 05期

关键词：

D O I：

10.1016/S0962-8924(97)01034-9

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

During meiosis, the pairing of chromosomes is crucial for a successful partitioning of the genetic material and its transmission into the developing gamete. The classical view of meiotic pairing involves recombination between homologues as art integral part of the pairing mechanism. But, in cases where no recombination occurs, how do chromosome partners find one another? And how do they pair up and then segregate appropriately? Recently, a combination of molecular genetics and fluorescence in situ hybridization appears to have provided an answer to these questions by demonstrating a crucial role for heterochromatin in chromosome pairing.

引用

页码：201 / 205

页数：5

共 40 条

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[2]

[Anonymous], 1988, Heterochromatin: Molecular an structural aspects

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