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Phase-transition polymers for drug delivery

被引：59
作者：
Yuk, SH
Bae, YH
机构：
[1] Kwangju Inst Sci & Technol, Dept Mat Sci & Engn, Puk Gu, Kwangju 500712, South Korea
[2] Han Nam Univ, Dept Polymer Sci & Engn, Taedeng Ku, Taejeon 306791, South Korea
来源：
CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS | 1999年 / 16卷 / 04期
关键词：
phase-transition polymer; external stimuli; modulated drug delivery;
D O I：
10.1615/CritRevTherDrugCarrierSyst.v16.i4.20
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Phase-transition polymers show changes in response to external stimuli, such as pH, temperature,light, metabolite, and electric current. Based on the stimuli-induced phase transition, many applications have been developed to improve drug delivery. This paper summarizes various phase-transition polymers and their applications relevant to modulated-drug delivery.
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收藏
页码：385 / 423
页数：39
相关论文
共 107 条
[1]   A POLYMERIC FILM RESPONDING IN DIFFUSION PROPERTIES TO ENVIRONMENTAL PH STIMULI - A MODEL FOR A SELF-REGULATING DRUG DELIVERY SYSTEM [J].
ALHAIQUE, F ;
MARCHETTI, M ;
RICCIERI, FM ;
SANTUCCI, E .
JOURNAL OF PHARMACY AND PHARMACOLOGY, 1981, 33 (07) :413-418
[2]  
[Anonymous], 1984, POLYM BIOMATERIALS, DOI [DOI 10.1007/978-1-4613-2433-1_14, 10.1007/978-1-4613-2433-1_14]
[3]   TEMPERATURE-RESPONSIVE INTERPENETRATING POLYMER NETWORKS CONSTRUCTED WITH POLY(ACRYLIC ACID) AND POLY(N,N-DIMETHYLACRYLAMIDE) [J].
AOKI, T ;
KAWASHIMA, M ;
KATONO, H ;
SANUI, K ;
OGATA, N ;
OKANO, T ;
SAKURAI, Y .
MACROMOLECULES, 1994, 27 (04) :947-952
[4]   Extracellular matrix for a rechargeable cell delivery system [J].
Bae, YH ;
Vernon, B ;
Han, CK ;
Kim, SW .
JOURNAL OF CONTROLLED RELEASE, 1998, 53 (1-3) :249-258
[5]  
BAE YH, 1987, MAKROMOL CHEM-RAPID, V8, P481
[6]   ON-OFF THERMOCONTROL OF SOLUTE TRANSPORT .2. SOLUTE RELEASE FROM THERMOSENSITIVE HYDROGELS [J].
BAE, YH ;
OKANO, T ;
KIM, SW .
PHARMACEUTICAL RESEARCH, 1991, 8 (05) :624-628
[7]   ON OFF THERMOCONTROL OF SOLUTE TRANSPORT .1. TEMPERATURE-DEPENDENCE OF SWELLING OF N-ISOPROPYLACRYLAMIDE NETWORKS MODIFIED WITH HYDROPHOBIC COMPONENTS IN WATER [J].
BAE, YH ;
OKANO, T ;
KIM, SW .
PHARMACEUTICAL RESEARCH, 1991, 8 (04) :531-537
[8]   TEMPERATURE-DEPENDENCE OF SWELLING OF CROSS-LINKED POLY(N,N'-ALKYL SUBSTITUTED ACRYLAMIDES) IN WATER [J].
BAE, YH ;
OKANO, T ;
KIM, SW .
JOURNAL OF POLYMER SCIENCE PART B-POLYMER PHYSICS, 1990, 28 (06) :923-936
[9]   INSULIN PERMEATION THROUGH THERMO-SENSITIVE HYDROGELS [J].
BAE, YH ;
OKANO, T ;
KIM, SW .
JOURNAL OF CONTROLLED RELEASE, 1989, 9 (03) :271-279
[10]  
BAE YH, 1988, MACROMOL RAPID, V9, P1985
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