Immunity following use of Australian tick fever vaccine: a review of the evidence

被引:78
作者
Bock, RE [1 ]
De Vos, AJ [1 ]
机构
[1] Queensland Dept Primary Ind, Tick Fever Res Ctr, Anim & Plant Hlth Serv, Wacol, Qld 4076, Australia
关键词
tick fever; Babesia bovis; Babesia bigemina; Anaplasma centrale; Anaplasma marginale; live cattle exports; vaccination;
D O I
10.1111/j.1751-0813.2001.tb10931.x
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Objective To review the evidence available on the degree and duration of immunity provided by Australian tick fever vaccines against Babesia bovis, B bigemina and Anaplasma marginale infections in Australia and overseas. Background Vaccines containing attenuated strains of B bovis and B bigemina as well as A centrale grown in splenectomised calves have been used in Australia since 1964 to immunise cattle against tick fever. About 800,000 doses of vaccine are supplied annually and much of the evidence for protection is field evidence rather than conventional immunological measures or pen trials. Conclusions Immunity to Babesia bovis and B bigemina - A single inoculation generally provides sound, long-lasting protection both in Australia and overseas. No evidence was found of a loss of immunity with time. Vaccine failures to B bovis do occur, but are uncommon and evidently caused by a number of factors, including immune responsiveness of the vaccinated animals, and immunogenicity of the vaccine strain. Immunity to Anaplasma marginale - The vaccine containing A centrale provides partial, variable protection against A marginate. Protection against challenge in Australia is adequate in most cases to prevent disease and use of the vaccine in this country appears to be justified. Protection against antigenically diverse, highly virulent stocks of A marginale in other countries is, at times, clearly inadequate and better vaccines are required in situations where the challenge is severe.
引用
收藏
页码:832 / 839
页数:8
相关论文
共 76 条
[1]   HETEROLOGOUS ANTIBODY-RESPONSES OF CALVES TO ANAPLASMA-CENTRALE AND A-MARGINALE [J].
ADAMS, JH ;
SHIELS, IA ;
DEVOS, AJ .
VETERINARY PARASITOLOGY, 1989, 31 (01) :7-12
[2]   The history of the cattle tick Boophilus microplus in Australia and achievements in its control [J].
Angus, BM .
INTERNATIONAL JOURNAL FOR PARASITOLOGY, 1996, 26 (12) :1341-1355
[3]  
[Anonymous], 1984, TICKS TICK BORNE DIS, V2
[4]   VACCINATION WITH ANAPLASMA-CENTRALE - RESPONSE AFTER AN EXPERIMENTAL CHALLENGE WITH ANAPLASMA-MARGINALE [J].
ANZIANI, OS ;
TARABLA, HD ;
FORD, CA ;
GALLETO, C .
TROPICAL ANIMAL HEALTH AND PRODUCTION, 1987, 19 (02) :83-87
[5]  
Bock R. E., 1997, CHALLENGING BOUNDARI, P175
[6]   STUDIES ON FAILURE OF T-STRAIN LIVE BABESIA-BOVIS VACCINE [J].
BOCK, RE ;
DEVOS, AJ ;
KINGSTON, TG ;
FRASER, IR .
AUSTRALIAN VETERINARY JOURNAL, 1995, 72 (08) :296-300
[7]   Effect of breed of cattle on transmission rate and innate resistance to infection with Babesia bovis and B bigemina transmitted by Boophilus microplus [J].
Bock, RE ;
Kingston, TG ;
de Vos, AJ .
AUSTRALIAN VETERINARY JOURNAL, 1999, 77 (07) :461-464
[8]   Effect of cattle breed on innate resistance to inoculations of Babesia bigemina [J].
Bock, RE ;
Kingston, TG ;
Standfast, NF ;
de Vos, AJ .
AUSTRALIAN VETERINARY JOURNAL, 1999, 77 (07) :465-466
[9]   Effect of breed of cattle on innate resistance to infection with Babesia bovis, B-bigemina and Anaplasma marginale [J].
Bock, RE ;
deVos, AJ ;
Kingston, TG ;
McLellan, DJ .
AUSTRALIAN VETERINARY JOURNAL, 1997, 75 (05) :337-340
[10]   INVESTIGATIONS OF BREAKDOWNS IN PROTECTION PROVIDED BY LIVING BABESIA-BOVIS VACCINE [J].
BOCK, RE ;
DEVOS, AJ ;
KINGSTON, TG ;
SHIELS, IA ;
DALGLIESH, RJ .
VETERINARY PARASITOLOGY, 1992, 43 (1-2) :45-56