Serum amyloid A (SAA): a concise review of biology, assay methods and clinical usefulness

被引：165

作者：

Yamada, T ^{[1
]}

机构：

[1] Jichi Med Sch, Dept Clin Pathol, Minami Kawachi, Tochigi 3290498, Japan

来源：

CLINICAL CHEMISTRY AND LABORATORY MEDICINE | 1999年 / 37卷 / 04期

关键词：

serum amyloid A; inflammation; assay method; clinical significance; C-reactive protein;

D O I：

10.1515/CCLM.1999.063

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Serum amyloid A (SAA) is a family of proteins encoded in a multigene complex. Acute phase isotypes SAA1 and SAA2 are synthesized in response to inflammatory cytokines. SAA and C-reactive protein (CRP) are now the most sensitive indicators for assessing inflammatory activity. In viral infection and kidney allograft rejection, SAA proved more useful than CRP. Development of convenient assay methods for SAA will facilitate its use in clinical laboratories.

引用

页码：381 / 388

页数：8

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