Selective reductions of nitroarenes to anilines using metallic zinc in near-critical water

被引：34

作者：

Boix, C ^{[1
]}

Poliakoff, N ^{[1
]}

机构：

[1] Univ Nottingham, Sch Chem, Nottingham NG7 2RD, England

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1999年 / 11期

关键词：

D O I：

10.1039/a901271k

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new procedure for the preparation of anilines (2) in good yield by reduction of the corresponding nitroarenes (1) using Zn in H2O at 220-300 degrees C is described. The procedure is powerful enough to reduce sterically hindered 2-nitro-m-xylene (1c) and is chemoselective for the NO2 groups in 1-chloro-2-nitrobenzene (1d) and 1-nitro-3-vinylbenzene (1h). The process involves the reduction of H2O by Zn to generate H-2 followed by hydrogenation of the NO2 group catalysed by residual traces of Zn.

引用

页码：1487 / 1490

页数：4

共 29 条

[1] Applications of high-temperature aqueous media for synthetic organic reactions [J].