Revealing the Incidentalome When Targeting the Tumor Genome

被引：51

作者：

Bombard, Yvonne ^{[1
,2
,3
]}

Robson, Mark ^{[1
,4
]}

Offit, Kenneth ^{[1
,5
,6
]}

机构：

[1] Mem Sloan Kettering Canc Ctr, Clin Genet Serv, Dept Med, New York, NY 10021 USA

[2] Mem Sloan Kettering Canc Ctr, Ctr Hlth Policy & Outcomes, Dept Epidemiol & Biostat, New York, NY 10021 USA

[3] Yale Univ, Dept Epidemiol & Publ Hlth, Sch Publ Hlth, New Haven, CT 06520 USA

[4] Weill Cornell Med Coll, Dept Med, New York, NY USA

[5] Weill Cornell Med Coll, Mem Sloan Kettering Canc Ctr, Sloan Kettering Inst, Canc Biol & Genet Program,Dept Med, New York, NY USA

[6] Weill Cornell Med Coll, Dept Publ Hlth, New York, NY USA

来源：

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION | 2013年 / 310卷 / 08期

关键词：

PATIENT AUTONOMY; RISKS; DUTY; WARN;

D O I：

10.1001/jama.2013.276573

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

引用

页码：795 / 796

页数：2

共 8 条

[1]

Bombard Y, 2013, EUR J HUM GENET

[2]

Risks to Relatives in Genomic Research: A Duty to Warn? [J].

Bombard, Yvonne ;

Offit, Kenneth ;

Robson, Mark E. .

AMERICAN JOURNAL OF BIOETHICS, 2012, 12 (10) :12-14

[3]

Description and pilot results from a novel method for evaluating return of incidental findings from next-generation sequencing technologies [J].

Goddard, Katrina A. B. ;

Whitlock, Evelyn P. ;

Berg, Jonathan S. ;

Williams, Marc S. ;

Webber, Elizabeth M. ;

Webster, Jennifer A. ;

Lin, Jennifer S. ;

Schrader, Kasmintan A. ;

Campos-Outcalt, Doug ;

Offit, Kenneth ;

Feigelson, Heather Spencer ;

Hollombe, Celine .

GENETICS IN MEDICINE, 2013, 15 (09) :721-728

[4]

ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing [J].

Green, Robert C. ;

Berg, Jonathan S. ;

Grody, Wayne W. ;

Kalia, Sarah S. ;

Korf, Bruce R. ;

Martin, Christa L. ;

McGuire, Amy L. ;

Nussbaum, Robert L. ;

O'Daniel, Julianne M. ;

Ormond, Kelly E. ;

Rehm, Heidi L. ;

Watson, Michael S. ;

Williams, Marc S. ;

Biesecker, Leslie G. .

GENETICS IN MEDICINE, 2013, 15 (07) :565-574

[5]

Return of Secondary Genomic Findings vs Patient Autonomy Implications for Medical Care [J].

Klitzman, Robert ;

Appelbaum, Paul S. ;

Chung, Wendy .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2013, 310 (04) :369-370

[6]

The "duty to warn" a patient's family members about hereditary disease risks [J].

Offit, K ;

Groeger, E ;

Turner, S ;

Wadsworth, EA ;

Weiser, MA .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2004, 292 (12) :1469-1473

[7]

Whole-Genome Sequencing A Step Closer to Personalized Medicine [J].

Pasche, Boris ;

Absher, Devin .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2011, 305 (15) :1596-1597

[8]

Mandatory Extended Searches in All Genome Sequencing "Incidental Findings," Patient Autonomy, and Shared Decision Making [J].

Ross, Lainie Friedman ;

Rothstein, Mark A. ;

Clayton, Ellen Wright .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2013, 310 (04) :367-368

← 1 →