Acute Heart Failure Syndromes in Patients With Coronary Artery Disease Early Assessment and Treatment

被引:99
作者
Flaherty, James D. [1 ]
Bax, Jeroen J. [2 ]
De Luca, Leonardo [3 ]
Rossi, Joseph S. [1 ]
Davidson, Charles J. [1 ]
Filippatos, Gerasimos [4 ]
Liu, Peter P. [5 ]
Konstam, Marvin A. [6 ]
Greenberg, Barry [7 ]
Mehra, Mandeep R. [8 ]
Breithardt, Guenter [9 ]
Pang, Peter S. [10 ]
Young, James B. [11 ]
Fonarow, Gregg C. [12 ]
Bonow, Robert O. [1 ]
Gheorghiade, Mihai [1 ]
机构
[1] Northwestern Univ, Feinberg Sch Med, Div Cardiol, Dept Med, Chicago, IL 60611 USA
[2] Leiden Univ, Med Ctr, Dept Cardiol, Univ Hosp, Leiden, Netherlands
[3] European Hosp, Dept Cardiol, Rome, Italy
[4] Attikon Univ Hosp, Dept Cardiol, Athens, Greece
[5] UHN, Toronto Gen Hosp, Dept Cardiol, Toronto, ON, Canada
[6] Tufts Univ, Sch Med, Div Cardiol, Boston, MA 02111 USA
[7] Univ Calif San Diego, Dept Cardiol, San Diego, CA 92103 USA
[8] Univ Maryland, Sch Med, Div Cardiol, Baltimore, MD 21201 USA
[9] Hosp Univ Munster, Dept Cardiol & Angiol, Munster, Germany
[10] Northwestern Univ, Feinberg Sch Med, Dept Emergency Med, Chicago, IL 60611 USA
[11] Cleveland Clin Fdn, Dept Cardiovasc Med, Heart Failure Sect, Cleveland, OH 44195 USA
[12] Univ Calif Los Angeles, Dept Med, Los Angeles, CA 90024 USA
基金
美国国家卫生研究院;
关键词
acute heart failure; coronary artery disease; assessment; ACUTE MYOCARDIAL-INFARCTION; LEFT-VENTRICULAR DYSFUNCTION; INITIATE LIFESAVING TREATMENT; PRESERVED EJECTION FRACTION; CARDIAC TROPONIN-I; NATIONAL-REGISTRY; OPTIMIZE-HF; CLINICAL CHARACTERISTICS; HIBERNATING MYOCARDIUM; HOSPITALIZED-PATIENTS;
D O I
10.1016/j.jacc.2008.08.072
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Acute heart failure syndromes (AHFS) have emerged as a leading public health problem worldwide, accounting for a substantial number of hospitalizations and a high utilization of resources. Although in-hospital mortality rates are relatively low, patients with AHFS have very high early after-discharge mortality and rehospitalization rates. The majority of patients admitted with AHFS have coronary artery disease (CAD), which independently has an adverse impact on prognosis. The initial in-hospital and after-discharge management of AHFS may be dependent on clinical presentation: AHFS in patients with underlying CAD or acute coronary syndromes (ACS) complicated by heart failure. In addition, the extent and severity of CAD and the presence of ischemia and/or stunned/hibernating myocardium should be assessed for optimal management. Although the overall management of AHFS with CAD may be similar to that in patients with ACS complicated by heart failure, for which specific guidelines exist, management of the former is less well defined. Prospective studies of the assessment and treatment of CAD in patients with AHFS are urgently needed. (J Am Coll Cardiol 2009;53:254-63) (c) 2009 by the American College of Cardiology Foundation
引用
收藏
页码:254 / 263
页数:10
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