Osteoporosis Diagnosis and Medical Treatment

被引：70

作者：

Warriner, Amy H. ^{[1
,3
]}

Saag, Kenneth G. ^{[2
]}

机构：

[1] Univ Alabama Birmingham, Div Endocrinol Metab & Diabet, Birmingham, AL 35233 USA

[2] Univ Alabama Birmingham, Div Clin Immunol & Rheumatol, Dept Med, Birmingham, AL 35233 USA

[3] Univ Alabama Birmingham, Div Endocrinol Diabet & Metab, Dept Med, Birmingham, AL 35233 USA

来源：

ORTHOPEDIC CLINICS OF NORTH AMERICA | 2013年 / 44卷 / 02期

关键词：

Osteoporosis; Treatment; Prevention; Diagnosis; Update; RANDOMIZED CONTROLLED-TRIAL; VITAMIN-D SUPPLEMENTATION; BONE-MINERAL DENSITY; PLACEBO-CONTROLLED TRIAL; FORCE RECOMMENDATION STATEMENT; CLINICAL-PRACTICE GUIDELINE; VERTEBRAL FRACTURE RISK; NURSING-HOME RESIDENTS; HIGH-TRAUMA FRACTURES; HEALTHY OLDER WOMEN;

D O I：

10.1016/j.ocl.2013.01.005

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

100224 [整形外科学];

摘要：

Osteoporosis, the presence of either low bone mineral density or a history of a fragility fracture, is known to be associated with an increased risk of future fracture. Fracture prevention is possible through use of both nonpharmacologic and prescription treatments. Despite recent controversy regarding the safety of calcium supplementation and the appropriate dosing of calcium and vitamin D, calcium and vitamin D remain an important part of bone health. However, prescription osteoporosis treatments should be considered for those at higher risk for fracture, and there are currently several treatment options available.

引用

页码：125 / +

页数：12

共 76 条

[1]

A single-dose placebo-controlled study of AMG 162, a fully human monoclonal antibody to RANKL, in postmenopausal women [J].

Bekker, PJ ;

Holloway, DL ;

Rasmussen, AS ;

Murphy, R ;

Martin, SW ;

Leese, PT ;

Holmes, GB ;

Dunstan, CR ;

DePaoli, AM .

JOURNAL OF BONE AND MINERAL RESEARCH, 2005, 20 (12) :2274-2282

[2]

Effects of vitamin D and calcium supplementation on falls:: A randomized controlled trial [J].

Bischoff, HA ;

Stähelin, HB ;

Dick, W ;

Akos, R ;

Knecht, M ;

Salis, C ;

Nebiker, M ;

Theiler, R ;

Pfeifer, M ;

Begerow, B ;

Lew, RA ;

Conzelmann, M .

JOURNAL OF BONE AND MINERAL RESEARCH, 2003, 18 (02) :343-351

[3]

Bischoff-Ferrari HA, 2006, ARCH INTERN MED, V166, P424

[4]

Fracture prevention with vitamin D supplementation - A meta-analysis of randomized controlled trials [J].

Bischoff-Ferrari, HA ;

Willett, WC ;

Wong, JB ;

Giovannucci, E ;

Dietrich, T ;

Dawson-Hughes, B .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2005, 293 (18) :2257-2264

[5]

A Pooled Analysis of Vitamin D Dose Requirements for Fracture Prevention [J].

Bischoff-Ferrari, Heike A. ;

Willett, Walter C. ;

Orav, Endel J. ;

Lips, Paul ;

Meunier, Pierre J. ;

Lyons, Ronan A. ;

Flicker, Leon ;

Wark, John ;

Jackson, Rebecca D. ;

Cauley, Jane A. ;

Meyer, Haakon E. ;

Pfeifer, Michael ;

Sanders, Kerrie M. ;

Stahelin, Hannes B. ;

Theiler, Robert ;

Dawson-Hughes, Bess .

NEW ENGLAND JOURNAL OF MEDICINE, 2012, 367 (01) :40-49

[6]

Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis [J].

Black, Dennis M. ;

Delmas, Pierre D. ;

Eastell, Richard ;

Reid, Ian R. ;

Boonen, Steven ;

Cauley, Jane A. ;

Cosman, Felicia ;

Lakatos, Peter ;

Leung, Ping Chung ;

Man, Zulema ;

Mautalen, Carlos ;

Mesenbrink, Peter ;

Hu, Huilin ;

Caminis, John ;

Tong, Karen ;

Rosario-Jansen, Theresa ;

Krasnow, Joel ;

Hue, Trisha F. ;

Sellmeyer, Deborah ;

Eriksen, Erik Fink ;

Cummings, Steven R. .

NEW ENGLAND JOURNAL OF MEDICINE, 2007, 356 (18) :1809-1822

[7]

Continuing Bisphosphonate Treatment for Osteoporosis - For Whom and for How Long? [J].

Black, Dennis M. ;

Bauer, Douglas C. ;

Schwartz, Ann V. ;

Cummings, Steven R. ;

Rosen, Clifford J. .

NEW ENGLAND JOURNAL OF MEDICINE, 2012, 366 (22) :2051-2053

[8]

Vascular events in healthy older women receiving calcium supplementation: randomised controlled trial [J].

Bolland, Mark J. ;

Barber, P. Alan ;

Doughty, Robert N. ;

Mason, Barbara ;

Horne, Anne ;

Ames, Ruth ;

Gamble, Gregory D. ;

Grey, Andrew ;

Reid, Ian R. .

BMJ-BRITISH MEDICAL JOURNAL, 2008, 336 (7638) :262-266

[9]

Calcium supplements with or without vitamin D and risk of cardiovascular events: reanalysis of the Women's Health Initiative limited access dataset and meta-analysis [J].

Bolland, Mark J. ;

Grey, Andrew ;

Avenell, Alison ;

Gamble, Greg D. ;

Reid, Ian R. .

BMJ-BRITISH MEDICAL JOURNAL, 2011, 342

[10]

Effect of calcium supplements on risk of myocardial infarction and cardiovascular events: meta-analysis [J].

Bolland, Mark J. ;

Avenell, Alison ;

Baron, John A. ;

Grey, Andrew ;

MacLennan, Graeme S. ;

Gamble, Greg D. ;

Reid, Ian R. .

BMJ-BRITISH MEDICAL JOURNAL, 2010, 341 :289

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