Solid state and solution structural studies of chiral phosphoramide-tin complexes relevant to Lewis base catalyzed aldol reactions

被引：46

作者：

Denmark, SE ^{[1
]}

Su, XP ^{[1
]}

机构：

[1] Univ Illinois, Dept Chem, Roger Adams Lab, Urbana, IL 61801 USA

来源：

TETRAHEDRON | 1999年 / 55卷 / 29期

关键词：

phosphoramides; tin and compounds; X-ray crystal structures; aldol reactions;

D O I：

10.1016/S0040-4020(99)00439-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Complexes of chiral phosphoramides 4 and 5 with tin-based Lewis acids were studied by both X-ray crystallography and low temperature Sn-119, NMR spectroscopy. The structure of a ternary complex between 5, SnCl4 and benzaldehyde was also obtained and provided a detailed view of the binding of both aldehyde and phosphoramide to Lewis acids. Sn-119 NMR, spectroscopy indicated that a 2/1 stoichiometry of phosphoramide to tin is favored in solution as well. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：8727 / 8738

页数：12

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