Adaptive thermogenesis: Orchestrating mitochondrial biogenesis

被引:28
作者
Butow, RA [1 ]
Bahassi, EM [1 ]
机构
[1] Univ Texas, SW Med Ctr, Dept Mol Biol, Dallas, TX 75235 USA
关键词
D O I
10.1016/S0960-9822(00)80008-1
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The biogenesis of mitochondria requires products of the nuclear and mitochondrial genomes. Recent studies of adaptive thermogenesis have shown how mitochondrial proliferation and respiratory activity in brown fat and skeletal muscle are directed by the transcriptional coactivator PGC-1.
引用
收藏
页码:R767 / R769
页数:3
相关论文
共 15 条
  • [1] MOUSE RNASE MRP RNA IS ENCODED BY A NUCLEAR GENE AND CONTAINS A DECAMER SEQUENCE COMPLEMENTARY TO A CONSERVED REGION OF MITOCHONDRIAL RNA SUBSTRATE
    CHANG, DD
    CLAYTON, DA
    [J]. CELL, 1989, 56 (01) : 131 - 139
  • [2] TERMINATION OF TRANSCRIPTION IN HUMAN MITOCHONDRIA - IDENTIFICATION AND PURIFICATION OF A DNA-BINDING PROTEIN FACTOR THAT PROMOTES TERMINATION
    KRUSE, B
    NARASIMHAN, N
    ATTARDI, G
    [J]. CELL, 1989, 58 (02) : 391 - 397
  • [3] Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice
    Larsson, NG
    Wang, JM
    Wilhelmsson, H
    Oldfors, A
    Rustin, P
    Lewandoski, M
    Barsh, GS
    Clayton, DA
    [J]. NATURE GENETICS, 1998, 18 (03) : 231 - 236
  • [4] Adaptive thermogenesis: Turning on the heat
    Lowell, BB
    [J]. CURRENT BIOLOGY, 1998, 8 (15) : R517 - R520
  • [5] The high mobility group protein Abf2p influences the level of yeast mitochondrial DNA recombination intermediates in vivo
    MacAlpine, DM
    Perlman, PS
    Butow, RA
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (12) : 6739 - 6743
  • [6] NICHOLLS DG, 1983, PHYSIOL REV, V64, P1
  • [7] A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
    Puigserver, P
    Wu, ZD
    Park, CW
    Graves, R
    Wright, M
    Spiegelman, BM
    [J]. CELL, 1998, 92 (06) : 829 - 839
  • [8] Nuclear control of respiratory chain expression in mammalian cells
    Scarpulla, RC
    [J]. JOURNAL OF BIOENERGETICS AND BIOMEMBRANES, 1997, 29 (02) : 109 - 119
  • [9] Differential expression of mitochondrial DNA replication factors in mammalian tissues
    Schultz, RA
    Swoap, SJ
    McDaniel, LD
    Zhang, BQ
    Koon, EC
    Garry, DJ
    Li, K
    Williams, RS
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (06) : 3447 - 3451
  • [10] SHADEL GS, 1993, J BIOL CHEM, V268, P16083