Retention behaviour of products extracted from oriental medicine formulations in high-performance liquid chromatography on octadecyl acrylate-modified silicas

被引：5

作者：

Okamoto, M

Kato, M

Nobuhara, K

Satoh, K

Yamamoto, Y

Ihara, H

机构：

[1] Gifu Prefectural Gero Spa Hosp, Gifu 5092292, Japan

[2] Fuji Silysia Chem Ltd, Miyazaki 8830062, Japan

[3] Tochimoto Tenkaido Ltd, Osaka 5300053, Japan

[4] Kumamoto Univ, Kumamoto 8600862, Japan

来源：

JOURNAL OF CHROMATOGRAPHY A | 1999年 / 845卷 / 1-2期

关键词：

pharmaceutical analysis; silica; bonded; octadecyl acrylate-modified silica; ginsenosides;

D O I：

10.1016/S0021-9673(99)00297-6

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

In this work, octadecyl acrylate (ODA) having a reactive group at one side of the terminal groups were synthesized and evaluated using the extract products in oriental medicine formulations by high-performance liquid chromatography (HPLC). By elemental analysis as well as IR and NMR spectroscopy, the average degree of polymerization of ODA-modified silicas were determined to be 19. Using acetonitrile-water mixtures as the eluent, ginsenosides Rbl and Rg1 in commercial Panax Ginseng or Red Ginseng were separated on ODA-modified silicas, but with different degrees of resolution comparing with ODS-modified silicas. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：409 / 415

页数：7

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