Clinical outcome and B cell depletion in patients with rheumatoid arthritis receiving rituximab monotherapy in comparison with patients receiving concomitant methotrexate

被引:23
作者
Owczarczyk, K. [1 ]
Hellmann, M. [1 ]
Fliedner, G.
Roehrs, T. [1 ]
Maizus, K. [1 ]
Passon, D. [2 ]
Hallek, M. [1 ]
Rubbert, A. [1 ]
机构
[1] Univ Hosp Cologne, Div Rheumatol, Dept Med, D-50924 Cologne, Germany
[2] Univ Cologne, Immunol Lab, Inst Pharmacol, Cologne, Germany
关键词
D O I
10.1136/ard.2007.087023
中图分类号
R5 [内科学];
学科分类号
1002 [临床医学]; 100201 [内科学];
摘要
引用
收藏
页码:1648 / 1650
页数:5
相关论文
共 6 条
[1]
Rituximab for rheumatoid arthritis refractory to anti-tumor necrosis factor therapy - Results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial evaluating primary efficacy and safety at twenty-four weeks [J].
Cohen, Stanley B. ;
Emery, Paul ;
Greenwald, Maria W. ;
Dougados, Maxime ;
Furie, Richard A. ;
Genovese, Mark C. ;
Keystone, Edward C. ;
Loveless, James E. ;
Burmester, Gerd-Ruediger ;
Cravets, Matthew W. ;
Hessey, Eva W. ;
Shaw, Timothy ;
Totoritis, Mark C. .
ARTHRITIS AND RHEUMATISM, 2006, 54 (09) :2793-2806
[2]
Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis [J].
Edwards, JCW ;
Szczepanski, L ;
Szechinski, J ;
Filipowicz-Sosnowska, A ;
Emery, P ;
Close, DR ;
Stevens, RM ;
Shaw, T .
NEW ENGLAND JOURNAL OF MEDICINE, 2004, 350 (25) :2572-2581
[3]
The efficacy and safety of rituximab in patients with active rheumatoid arthritis despite methotrexate treatment - Results of a phase IIb randomized, double-blind, placebo-controlled, dose-ranging trial [J].
Emery, P ;
Fleischmann, R ;
Filipowicz-Sosnowska, A ;
Schechtman, J ;
Szczepanski, L ;
Kavanaugh, A ;
Racewicz, AJ ;
Van Vollenhoven, RF ;
Li, NF ;
Agarwal, S ;
Hessey, EW ;
Shaw, TM .
ARTHRITIS AND RHEUMATISM, 2006, 54 (05) :1390-1400
[4]
Regeneration of B cell subsets after transient B cell depletion using anti-CD20 antibodies in rheumatoid arthritis [J].
Roll, Petra ;
Palanichamy, Arumugam ;
Kneitz, Christian ;
Dorner, Thomas ;
Tony, Hans-Peter .
ARTHRITIS AND RHEUMATISM, 2006, 54 (08) :2377-2386
[5]
Consensus statement on the use of rituximab in patients with rheumatoid arthritis [J].
Smolen, J. S. ;
Keystone, E. C. ;
Emery, P. ;
Breedveld, F. C. ;
Betteridge, N. ;
Burmester, G. R. ;
Dougados, M. ;
Ferraccioli, G. ;
Jaeger, U. ;
Klareskog, L. ;
Kvien, T. K. ;
Martin-Mola, E. ;
Pavelka, K. .
ANNALS OF THE RHEUMATIC DISEASES, 2007, 66 (02) :143-150
[6]
Development and validation of the European League Against Rheumatism response criteria for rheumatoid arthritis - Comparison with the preliminary American College of Rheumatology and the World Health Organization International League Against Rheumatism criteria [J].
vanGestel, AM ;
Prevoo, MLL ;
vantHof, MA ;
vanRijswijk, MH ;
vandePutte, LBA ;
vanRiel, PLCM .
ARTHRITIS AND RHEUMATISM, 1996, 39 (01) :34-40