Trendspotting in the Protein Data Bank

被引:67
作者
Berman, Helen M. [1 ]
Narayanan, Buvaneswari Coimbatore [1 ]
Di Costanzo, Luigi [1 ]
Dutta, Shuchismita [1 ]
Ghosh, Sutapa [1 ]
Hudson, Brian P. [1 ]
Lawson, Catherine L. [1 ]
Peisach, Ezra [1 ]
Prlic, Andreas [2 ]
Rose, Peter W. [2 ]
Shao, Chenghua [1 ]
Yang, Huanwang [1 ]
Young, Jasmine [1 ]
Zardecki, Christine [1 ]
机构
[1] Rutgers State Univ, Dept Chem & Chem Biol, Ctr Integrat Prote Res, Piscataway, NJ 08854 USA
[2] Univ Calif San Diego, San Diego Supercomp Ctr, La Jolla, CA 92093 USA
基金
美国国家科学基金会; 美国国家卫生研究院;
关键词
Protein; Nucleic acid; Database; Trend; 3-DIMENSIONAL STRUCTURE; CRYSTAL-STRUCTURE; REFINEMENT; VIRUS; RESOURCE; DIFFRACTION; DEPOSITION; BINDING; DESIGN; WWPDB;
D O I
10.1016/j.febslet.2012.12.029
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
070307 [化学生物学]; 071010 [生物化学与分子生物学];
摘要
The Protein Data Bank (PDB) was established in 1971 as a repository for the three dimensional structures of biological macromolecules. Since then, more than 85000 biological macromolecule structures have been determined and made available in the PDB archive. Through analysis of the corpus of data, it is possible to identify trends that can be used to inform us abou the future of structural biology and to plan the best ways to improve the management of the ever-growing amount of PDB data. (C) 2013 Federation of European Biochemical Societies. Published by Elsevier B. V. All rights reserved.
引用
收藏
页码:1036 / 1045
页数:10
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