A new efficient synthesis of pyridines

被引:37
作者
DeKimpe, N
Keppens, M
Fonck, G
机构
[1] Department of Organic Chemistry, Fac. of Agric. and Appl. Biol. Sci., University of Gent, B-9000 Gent
关键词
D O I
10.1039/cc9960000635
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Cyclic six-membered imines, i.e. 2,3,4,5-tetrahydropyridines, are efficiently converted under mild conditions into the corresponding pyridines by highly regioselective alpha, alpha-dichlorination with N-chlorosuccinimide (NCS) followed by double dehydrochlorination with methanolic bases.
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页码:635 / 636
页数:2
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