Application of molecular topology to liquid viscosity prediction for a group of organic compounds

Molecular Topology has been applied to search for a mathematical model able to predict liquid viscosity values for an extensive group of organic compounds with C, H, O, N, S and halogenous atoms. The topological descriptors we have used are the connectivity indices from Kier et Hall -up to fourth order-, and the electrotopological indices. Quality of regression equation finally selected has been evaluated by a crossvalidation study.. Viscosity of ail compounds excepted 1,1,2-trichlorotrifluoro etane is correctly predicted by the model proposed.