Prediction of gene function in methylthioadenosine recycling from regulatory signals

被引：41

作者：

Murphy, BA ^{[1
]}

Grundy, FJ ^{[1
]}

Henkin, TM ^{[1
]}

机构：

[1] Ohio State Univ, Dept Microbiol, Columbus, OH 43210 USA

来源：

JOURNAL OF BACTERIOLOGY | 2002年 / 184卷 / 08期

关键词：

D O I：

10.1128/JB.184.8.2314-2318.2002

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The S-box transcription termination control system, first identified in Bacillus subtilis, is used for regulation of gene expression in response to methionine availability. The presence of the S-box motif provided the first indication that the ykrTS and ykrW= genes could play a role in recycling of 5'-methylthioadenosine, a by-product of polyamine biosynthesis that can be converted to methionine. In this study we demonstrate a role for the ykrTS and ykrWXYZ gene products in this pathway.

引用

页码：2314 / 2318

页数：5

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