Daphnicyclidins A-H, novel hexa- or pentacyclic alkaloids from two species of Daphniphyllum

被引：87

作者：

Kobayashi, J ^{[1
]}

Inaba, Y

Shiro, M

Yoshida, N

Morita, H

机构：

[1] Hokkaido Univ, Grad Sch Pharmaceut Sci, Sapporo, Hokkaido 0600812, Japan

[2] Rigaku Corp, Xray Res Lab, Akishima, Tokyo 1968666, Japan

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2001年 / 123卷 / 46期

关键词：

D O I：

10.1021/ja016955e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Eight highly modified Daphniphyllum alkaloids with unprecedented fused hexa- or pentacyclic skeletons, daphnicyclidins A-H (1-8), have been isolated from the stems of Daphniphyllum humile and D. teijsmanni, and their structures were elucidated on the basis of spectroscopic data and chemical means. The stereochemistry was elucidated by combination of NOESY correlations, X-ray crystallographic data, and CD analyses.

引用

页码：11402 / 11408

页数：7

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