Recurrence of allergic bronchopulmonary aspergillosis in the posttransplant lungs of a cystic fibrosis patient

被引:25
作者
Fitzsimons, EJ
Aris, R
Patterson, R
机构
[1] NW MEM HOSP, DEPT MED, DIV ALLERGY IMMUNOL, CHICAGO, IL 60611 USA
[2] NW MEM HOSP, ERNEST S BAZLEY ASTHMA & ALLERGY DIS CTR, CHICAGO, IL 60611 USA
[3] UNIV N CAROLINA, CHAPEL HILL, NC USA
关键词
allergic bronchopulmonary aspergillosis; cystic fibrosis; lung transplant;
D O I
10.1378/chest.112.1.281
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Cystic fibrosis (CF) is an autosomal recessive disease of exocrine origin. Allergic bronchopulmonary aspergillosis (ABPA) is an immunologic disorder caused by colonization of the airways with Aspergillus fumigatus. A fumigatus has been cultured from posttransplant lungs in CF patients. Colonization of posttransplant lung with Aspergillus is a recognized phenomenon. In this case report, however, we present a patient who developed ABPA both before and after lung transplant. This patient meets the criteria for ABPA based on serologic results. ABPA may be a complication in post-CF lung transplant patients and serologic analysis should be considered when eosinophilia and pulmonary infiltrates or decline in lung function occurs.
引用
收藏
页码:281 / 282
页数:2
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