Acremoxanthones A and B, novel antibiotic polyketides from the fungus Acremonium sp BCC 31806

被引：32

作者：

Isaka, Masahiko ^{[1
]}

Palasarn, Somporn ^{[1
]}

Auncharoen, Patchanee ^{[1
]}

Kornmijit, Somjit ^{[1
]}

Jones, E. B. Gareth ^{[1
]}

机构：

[1] Natl Ctr Genet Engn & Biotechnol BIOTEC, Klongluang 12120, Pathumthani, Thailand

来源：

TETRAHEDRON LETTERS | 2009年 / 50卷 / 03期

关键词：

Acremonium sp; Acremoxanthone; Acremonidin; Antimalarial; Cytotoxicity; CERCOSPORA-BETICOLA; HUMICOLA SP; XANTHOQUINODINS; BIOSYNTHESIS;

D O I：

10.1016/j.tetlet.2008.10.146

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学];

摘要：

Acremoxanthones A and B, novel anthraquinone-xanthone heterodimers with a unique linkage pattern, together with two known compounds, acremonidins A and C, were isolated from the fungus Acremonium sp. BCC 31806. The structures of the acremoxanthones were determined by analysis of 2D NMR and mass spectrometric data. Acremoxanthones and acremonidins exhibited antibacterial, antifungal, antiplasmodial, and cytotoxic activities. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：284 / 287

页数：4

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