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Transcription: Tantalizing times for T cells

被引：199
作者：
Ho, IC
Glimcher, LH
机构：
[1] Harvard Univ, Sch Publ Hlth, Dept Immunol & Infect Dis, Boston, MA 02115 USA
[2] Harvard Univ, Sch Med, Dept Med, Boston, MA 02115 USA
来源：
CELL | 2002年 / 109卷
关键词：
D O I：
10.1016/S0092-8674(02)00705-5
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The T helper lymphocyte is responsible for orchestrating an appropriate immune response to pathogens. To do so, it has evolved into two specialized subsets that direct type 1 and type 2 immunity. Here, we discuss the genetic programs that control lineage commitment of progenitor T helper cells along each of these pathways.
引用
收藏
页码：S109 / S120
页数：12
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