COVID-19 as a STING disorder with delayed over-secretion of interferon-beta

被引：53

作者：

Berthelot, Jean-Marie ^{[1
]}

Liote, Frederic ^{[2
,3
]}

机构：

[1] Nantes Univ Hosp, Dept Rheumatol, Hotel Dieu,Pl Alexis Ricordeau, F-44093 Nantes 01, France

[2] Univ Paris, Hop Lariboisiere, Dept Rheumatol, UFR Med, 2 Rue Ambroise Pare, F-75010 Paris, France

[3] Univ Paris, Hop Lariboisiere, Inserm UMR 1132, Ctr Viggo Petersen,UFR Med, 2 Rue Ambroise Pare, F-75010 Paris, France

来源：

EBIOMEDICINE | 2020年 / 56卷

关键词：

MITOCHONDRIAL-DNA;

D O I：

10.1016/j.ebiom.2020.102801

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

引用

页数：3

共 10 条

[1]

The cGAS-cGAMP-STING Pathway: A Molecular Link Between Immunity and Metabolism [J].

Bai, Juli ;

Liu, Feng .

DIABETES, 2019, 68 (06) :1099-1108

[2]

A Human Gain-of-Function STING Mutation Causes Immunodeficiency and Gammaherpesvirus-Induced Pulmonary Fibrosis in Mice [J].

Bennion, Brock G. ;

Ingle, Harshad ;

Ai, Teresa L. ;

Miner, Cathrine A. ;

Platt, Derek J. ;

Smith, Amber M. ;

Baldridge, Megan T. ;

Miner, Jonathan J. .

JOURNAL OF VIROLOGY, 2019, 93 (04)

[3]

Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology [J].

Channappanavar, Rudragouda ;

Perlman, Stanley .

SEMINARS IN IMMUNOPATHOLOGY, 2017, 39 (05) :529-539

[4]

First evidence for STING SNP R293Q being protective regarding obesity-associated cardiovascular disease in age-advanced subjects - a cohort study [J].

Hamann, Lutz ;

Szwed, Malgorzata ;

Mossakowska, Malgorzata ;

Chudek, Jerzy ;

Puzianowska-Kuznicka, Monika .

IMMUNITY & AGEING, 2020, 17 (01)

[5]

Activated STING in a Vascular and Pulmonary Syndrome [J].

Liu, Y. ;

Jesus, A. A. ;

Marrero, B. ;

Yang, D. ;

Ramsey, S. E. ;

Sanchez, G. A. Montealegre ;

Tenbrock, K. ;

Wittkowski, H. ;

Jones, O. Y. ;

Kuehn, H. S. ;

Lee, C. -C. R. ;

DiMattia, M. A. ;

Cowen, E. W. ;

Gonzalez, B. ;

Palmer, I. ;

DiGiovanna, J. J. ;

Biancotto, A. ;

Kim, H. ;

Tsai, W. L. ;

Trier, A. M. ;

Huang, Y. ;

Stone, D. L. ;

Hill, S. ;

Kim, H. J. ;

St Hilaire, C. ;

Gurprasad, S. ;

Plass, N. ;

Chapelle, D. ;

Horkayne-Szakaly, I. ;

Foell, D. ;

Barysenka, A. ;

Candotti, F. ;

Holland, S. M. ;

Hughes, J. D. ;

Mehmet, H. ;

Issekutz, A. C. ;

Raffeld, M. ;

McElwee, J. ;

Fontana, J. R. ;

Minniti, C. P. ;

Moir, S. ;

Kastner, D. L. ;

Gadina, M. ;

Steven, A. C. ;

Wingfield, P. T. ;

Brooks, S. R. ;

Rosenzweig, S. D. ;

Fleisher, T. A. ;

Deng, Z. ;

Boehm, M. .

NEW ENGLAND JOURNAL OF MEDICINE, 2014, 371 (06) :507-518

[6]

Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease [J].

Lood, Christian ;

Blanco, Luz P. ;

Purmalek, Monica M. ;

Carmona-Rivera, Carmelo ;

De Ravin, Suk S. ;

Smith, Carolyne K. ;

Malech, Harry L. ;

Ledbetter, Jeffrey A. ;

Elkon, Keith B. ;

Kaplan, Mariana J. .

NATURE MEDICINE, 2016, 22 (02) :146-153

[7]

TMEM173 variants and potential importance to human biology and disease [J].

Patel, Seema ;

Jin, Lei .

GENES AND IMMUNITY, 2019, 20 (01) :82-89

[8]

IFN-α2a or IFN-β1a in combination with ribavirin to treat Middle East respiratory syndrome coronavirus pneumonia: a retrospective study [J].

Shalhoub, Sarah ;

Farahat, Fayssal ;

Al-Jiffri, Abdullah ;

Simhairi, Raed ;

Shamma, Omar ;

Siddiqi, Nauman ;

Mushtaq, Adnan .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2015, 70 (07) :2129-2132

[9]

Mitochondrial DNA stress primes the antiviral innate immune response [J].

West, A. Phillip ;

Khoury-Hanold, William ;

Staron, Matthew ;

Tal, Michal C. ;

Pineda, Cristiana M. ;

Lang, Sabine M. ;

Bestwick, Megan ;

Duguay, Brett A. ;

Raimundo, Nuno ;

MacDuff, Donna A. ;

Kaech, Susan M. ;

Smiley, James R. ;

Means, Robert E. ;

Iwasaki, Akiko ;

Shadel, Gerald S. .

NATURE, 2015, 520 (7548) :553-+

[10]

Dampened STING-Dependent Interferon Activation in Bats [J].

Xie, Jiazheng ;

Li, Yang ;

Shen, Xurui ;

Goh, Geraldine ;

Zhu, Yan ;

Cui, Jie ;

Wang, Lin-Fa ;

Shi, Zheng-Li ;

Zhou, Peng .

CELL HOST & MICROBE, 2018, 23 (03) :297-+

← 1 →