CDX-2, a new marker for adenocarcinoma of gastrointestinal origin

被引:58
作者
Li, MK
Folpe, AL
机构
[1] Emory Univ, Dept Pathol & Lab Med, Atlanta, GA 30322 USA
[2] Univ Florida, Dept Pathol Immunol & Lab Med, Gainesville, FL USA
关键词
CDX-2; adenocarcinoma; immunohistochemistry; metastasis; intestinal metaplasia; dysplasia; adenoma;
D O I
10.1097/00125480-200403000-00004
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
CDX2-88 is a recently developed monoclonal antibody to the intestinal epithelia-specific nuclear transcription factor CDX2. CDX2 immunohistochemistry has recently been shown to be useful in establishing gastrointestinal origin in metastatic tumors and will likely become a useful addition to the standard panel of immunostains for carcinomas of unknown primary sites. This article reviews the previous studies of this new antibody.
引用
收藏
页码:101 / 105
页数:5
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