Relationship between sarcopenia and fracture risks in obese postmenopausal women

被引:26
作者
Aubertin-Leheudre, Mylene [1 ]
Lord, Christine
Labonte, Melissa [1 ]
Khalil, Abdelouahed [2 ]
Dionne, Isabelle J. [1 ]
机构
[1] Univ Sherbrooke, Fac Phys & Educ Sports, Res Ctr Aging, Sherbrooke, PQ J1H 4C4, Canada
[2] Univ Sherbrooke, Fac Med, Res Ctr Aging, Sherbrooke, PQ J1H 4C4, Canada
基金
加拿大健康研究院;
关键词
bone mass density; fat-free mass; menopause; obesity; osteoporosis;
D O I
10.1080/08952840801984964
中图分类号
R4 [临床医学]; R592 [老年病学];
学科分类号
1002 [临床医学]; 100203 [老年医学]; 100602 [中西医结合临床];
摘要
It is known that obesity is inversely correlated with fracture risk. It remains unclear if a low muscle mass (sarcopenia) modulates the relationship between obesity and bone mass density. Twenty-seven obese women were matched for total fat mass (+/- 0.5 kg) and age (+/- 4 yrs) and divided in 3 equal groups: class II sarcopenic, class I sarcopenic, and nonsarcopenic. Body composition (DXA) and dietary intake were measured. Our results suggest that obesity may offer some protection against osteoporosis, even in sarcopenic postmenopausal women. However, further studies are needed to examine the actual implication of these results on a clinical standpoint.
引用
收藏
页码:297 / 308
页数:12
相关论文
共 46 条
[1]
THE INFLUENCE OF MENOPAUSE AND HORMONAL REPLACEMENT THERAPY ON BODY CELL MASS AND BODY-FAT MASS [J].
ALOIA, JF ;
VASWANI, A ;
RUSSO, L ;
SHEEHAN, M ;
FLASTER, E .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1995, 172 (03) :896-900
[2]
RELATIONSHIP OF MENOPAUSE TO SKELETAL AND MUSCLE MASS [J].
ALOIA, JF ;
MCGOWAN, DM ;
VASWANI, AN ;
ROSS, P ;
COHN, SH .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 1991, 53 (06) :1378-1383
[3]
HRT provides no additional beneficial effect on sarcopenia in physically active postmenopausal women: a cross-sectional, observational study [J].
Aubertin-Leheudre, M ;
Audet, M ;
Goulet, EDB ;
Dionne, IJ .
MATURITAS, 2005, 51 (02) :140-145
[4]
Effect of sarcopenia on cardiovascular disease risk factors in obese postmenopausal women [J].
Aubertin-Leheudre, Mylene ;
Lord, Christine ;
Goulet, Eric D. B. ;
Khalil, Abdelouahed ;
Dionne, Isabelle J. .
OBESITY, 2006, 14 (12) :2277-2283
[5]
Associations of fat and muscle masses with bone mineral in elderly men and women [J].
Baumgartner, RN ;
Stauber, PM ;
Koehler, KM ;
Romero, L ;
Garry, PJ .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 1996, 63 (03) :365-372
[6]
Sarcopenic obesity predicts Instrumental Activities of Daily Living disability in the elderly [J].
Baumgartner, RN ;
Wayne, SJ ;
Waters, DL ;
Janssen, I ;
Gallagher, D ;
Morley, JE .
OBESITY RESEARCH, 2004, 12 (12) :1995-2004
[7]
Relationship between body composition and bone mineral content in young and elderly women [J].
Bedogni, G ;
Mussi, C ;
Malavolti, M ;
Borghi, A ;
Poli, M ;
Battistini, N ;
Salvioli, G .
ANNALS OF HUMAN BIOLOGY, 2002, 29 (05) :559-565
[8]
Differential effect of obesity on bone mineral density in White, Hispanic and African American women: A cross sectional study [J].
Castro J.P. ;
Joseph L.A. ;
Shin J.J. ;
Arora S.K. ;
Nicasio J. ;
Shatzkes J. ;
Raklyar I. ;
Erlikh I. ;
Pantone V. ;
Bahtiyar G. ;
Chandler L. ;
Pabon L. ;
Choudhry S. ;
Ghadiri N. ;
Gosukonda P. ;
Muniyappa R. ;
Von-Gicyzki H. ;
McFarlane S.I. .
Nutrition & Metabolism, 2 (1)
[9]
Bone mineral density and body composition in underweight and normal elderly subjects [J].
Coin, A ;
Sergi, G ;
Benincà, P ;
Lupoli, L ;
Cinti, G ;
Ferrara, L ;
Benedetti, G ;
Tomasi, G ;
Pisent, C ;
Enzi, G .
OSTEOPOROSIS INTERNATIONAL, 2000, 11 (12) :1043-1050
[10]
COIN A, 2008, EJCN, V62, P1