Healing a natural knockout of epithelial organogenesis

被引：9

作者：

Kere, J ^{[1
]}

Elomaa, O

机构：

[1] Karolinska Inst, Novum, Dept Biosci, S-14157 Huddinge, Sweden

[2] Clin Res Ctr, S-14157 Huddinge, Sweden

[3] Univ Helsinki, Dept Med Genet, Biomedicum Helsinki, FIN-00014 Helsinki, Finland

来源：

TRENDS IN MOLECULAR MEDICINE | 2002年 / 8卷 / 05期

关键词：

D O I：

10.1016/S1471-4914(02)02342-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Ectodermal dysplasias are a large group of rare genetic disorders with developmental abnormalities in skin, teeth, hair and nails. Many of them are clinically serious and impair the life of patients. The cloning of the gene for the most common of them, X-linked anhidrotic ectodermal dysplasia, in 1996 opened the door to dissect novel developmental pathways at the molecular level. Since then, several new genes and proteins with novel functions have been identified.

引用

页码：197 / 200

页数：4

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