A regio- and stereocontrolled method for preparing 3,3-diarylacrylamides

被引：10

作者：

Hay, LA ^{[1
]}

Mitchell, D ^{[1
]}

机构：

[1] ELI LILLY & CO,LILLY CORP CTR,LILLY RES LABS,CHEM PROC RES & DEV,INDIANAPOLIS,IN 46285

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 37期

关键词：

D O I：

10.1016/S0040-4039(97)01528-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Palladium-catalyzed hydroarylation of acetylenes provides regio- and stereodefined olefins. This methodology has been extended to arylpropiolamides where 3,3-diarylaclylamides are prepared stereospecifically. In an independent fashion, both the E- and Z-isomers were prepared by judicious choice of arylpropiolamide preparation and the palladium catalyzed hydroarylation reaction. (C) 1997 Elsevier Science Ltd.

引用

页码：6533 / 6536

页数：4

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