The total synthesis of the fungal metabolite diversonol

被引：83

作者：

Nising, CF ^{[1
]}

Ohnemüller, UK ^{[1
]}

Bräse, S ^{[1
]}

机构：

[1] Univ Karlsruhe, Inst Organ Chem, D-76131 Karlsruhe, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 02期

关键词：

diversonol; domino reactions; fungal metabolites; natural products; total synthesis;

D O I：

10.1002/anie.200502913

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Mission accomplished. The fungal metabolite diversonol has been synthesized for the first time. A key step in the total synthesis was the domino oxa-Michael-aldol condensation of salicylic aldehyde 1 and 4-hydroxycyclohexenone (2) that afforded the tricyclic scaffold of the target compound. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：307 / 309

页数：3

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