cis-Clerodandes from axenic cultures of the liverwort Scapania nemorea

被引：27

作者：

Geis, W ^{[1
]}

Buschauer, B ^{[1
]}

Becker, H ^{[1
]}

机构：

[1] Univ Saarlandes, D-66041 Saarbrucken, Germany

来源：

PHYTOCHEMISTRY | 1999年 / 51卷 / 05期

关键词：

Scapania nemorea; Scapaniaceae; jungermanniales; liverwort; Hepaticae; axenic culture; cis-clerodanes;

D O I：

10.1016/S0031-9422(99)00069-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Seven cis-clerodanes, (-)-cis-cleroda-3,13-dien-16-hydroxy-15,18-dioic acid-15,16-olide, (-)-cis-cleroda-1,3,13-trien-15,18-dioic acid-15,16-olide, (-)-cis-cleroda-1,3,13-trien-16-hydroxy-15,18-dioic acid-15,16-olide, (-)-cis-cleroda-1,3,13-trien-15-hydroxy-16,18-dioic acid-16,15-olide, (-)-15,16-epoxy-cis-cleroda-3,13(16),14-trien-12-hydroxy-18-oic acid-18,6 alpha-olide, (-)-cis-cleroda-3,13-dien-12,16-dihydroxy-15, 18-dioic acid-15,16: 18,6 alpha-diolide and (-)-cis-cleroda-3,13-dien-12,15-dihydroxy-16,17,18-trioic acid-16,15:18,6 alpha-diolide along with the 5-epi-nidoresedic acid have been isolated from axenic cultures of the liverwort Scapania nemorea. Furthermore, the enantiomers of the known 5-epi-hardwickiic acid and (+)-15,16-epoxy-cis-ent-cleroda-3,13(16),14-trien-12-hydroxy-18-oic acid-18,6 alpha-olide besides the already reported (-)-strictic acid could be identified. The structures were elucidated by extensive 1D and 2D NMR techniques. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：643 / 649

页数：7

共 23 条

[1]

ADAM KP, 1994, PHYTOCHEMISTRY, V35, P139, DOI 10.1016/S0031-9422(00)90522-3

[2] ANASTREPTENE, A COMMONLY ENCOUNTERED SESQUITERPENE OF LIVERWORTS (HEPATICAE) [J].