Synthesis of meso-2,4-diaminoglutaric acid.

被引:18
作者
Avenoza, A [1 ]
Cativiela, C [1 ]
Peregrina, JM [1 ]
Zurbano, MM [1 ]
机构
[1] UNIV ZARAGOZA, CSIC, INST CIENCIA MAT ARAGON, DEPT ORGAN CHEM, E-50009 ZARAGOZA, SPAIN
关键词
D O I
10.1016/0957-4166(96)00179-6
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
In order to synthesise meso-2,4-diaminoglutaric acid a synthetic route has been developed, starting from Garner's aldehyde, in which the key step is the hydrogenation of (Z)-(R)-3-tert-butoxycarbonyl-2,2-dimethyl-4-[2'-(benzamido)-2'- (methoxycarbonyl)ethenyl]-1,3-oxazolidine, followed by oxidation and further hydrolysis. (C) 1995 Elsevier Science Ltd
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页码:1555 / 1558
页数:4
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