Plasmodium falciparum in vitro susceptibility to antimalarial drugs in Casamance (southwestern Senegal) during the first 5 years of routine use of artesunate-amodiaquine

被引:17
作者
Agnamey, P
Brasseur, P
de Pecoulas, PE
Vaillant, M
Olliaro, P
机构
[1] Univ Paris 05, Hop Hotel Dieu, Lab Parasitol Mycol, UFR Hotel Dieu Broussais, Paris, France
[2] Inst Rech Dev, UR 077, Dakar, Senegal
[3] Univ Caen, Fac Pharm, F-14032 Caen, France
[4] Ctr Rech Publ Sante, Luxembourg, Luxembourg
[5] UNICEF UNDP WB WHO Special Programme Res & Traini, Geneva, Switzerland
[6] Univ Bordeaux 2, Unite 3677, F-33076 Bordeaux, France
关键词
D O I
10.1128/AAC.50.4.1531-1534.2006
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
We have monitored the in vitro sensitivities of Plasmodium falciparum isolates predeployment and during the deployment of artesunate plus amodiaquine treatment in Mlomp, Casamance (southwestern Senegal) during 2000 to 2004. Parasites remained susceptible to both drugs. Chloroquine resistance levels were high but stable. Quinine continues to be effective.
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页码:1531 / 1534
页数:4
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