A simple model for an amperometric channel biosensor

A simple model is presented for the channel biosensor where an oxidase enzyme layer is located upstream of a detector electrode. In this model the enzyme kinetics are restricted to the linear region. The model enables the elucidation of the parameters important in tuning the response of the biosensor. Two extreme regimes of operation are identified; the kinetically limited and mass transport limited regimes both provide features which overcome reproducibility problems associated with the classical enzyme electrode geometry. (C) 1999 Elsevier Science S.A. All rights reserved.