Direct biooxidation of arenes to corresponding catechols with E-coli JM109 (pDTG602).: Application to synthesis of combretastatins A-1 and B-1

被引：20

作者：

Bui, VP ^{[1
]}

Hudlicky, T ^{[1
]}

Hansen, TV ^{[1
]}

Stenstrom, Y ^{[1
]}

机构：

[1] Univ Florida, Dept Chem, Gainesville, FL 32611 USA

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 15期

基金：

美国国家科学基金会;

关键词：

biooxidation catechol; combretastatins; Suzuki-Miyaura coupling;

D O I：

10.1016/S0040-4039(02)00389-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Convergent syntheses of combretastatins A-1 and B-1 were accomplished via coupling of biocatalytically generated p-bromomethoxycatechol with trimethoxyphenylacetylene. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：2839 / 2841

页数：3

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