An ambiguous fast synapse: a new twist in the tale of two transmitters

被引：10

作者：

Salter, MW

De Koninck, Y

机构：

[1] Univ Toronto, Hosp Sick Children, Dept Physiol, Toronto, ON M5G 1X8, Canada

[2] McGill Univ, Dept Pharmacol & Therapeut, Montreal, PQ H3G 1Y6, Canada

来源：

NATURE NEUROSCIENCE | 1999年 / 2卷 / 03期

关键词：

D O I：

10.1038/6296

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Jo and Schlichter describe GABA and ATP corelease from the same presynaptic cell, which suggests that a dorsal horn synapse could be excitatory or inhibitory depending on its postsynaptic receptors or the amount of transmitter released.

引用

页码：199 / 200

页数：2

共 14 条

[1] DO SOME NERVE-CELLS RELEASE MORE THAN ONE TRANSMITTER
BURNSTOCK, G
[J]. NEUROSCIENCE, 1976, 1 (04) : 239 - 248
[2] DALE HENRY, 1935, PROC ROY SOC MED, V28, P319
[3] The effects of raising intracellular calcium on synaptic GABA(A) receptor-channels
De Koninck, Y
Mody, I
[J]. NEUROPHARMACOLOGY, 1996, 35 (9-10) : 1365 - 1374
[4] Eccles J. C, 1957, The Physiology of Nerve Cells
[5] CHEMICAL TRANSMISSION AND DALES PRINCIPLE
ECCLES, JC
[J]. PROGRESS IN BRAIN RESEARCH, 1986, 68 : 3 - 13
[6] Corelease of two fast neurotransmitters at a central synapse
Jonas, P
Bischofberger, J
Sandkühler, J
[J]. SCIENCE, 1998, 281 (5375) : 419 - 424
[7] FUNCTIONAL-STUDIES OF COTRANSMISSION
KUPFERMANN, I
[J]. PHYSIOLOGICAL REVIEWS, 1991, 71 (03) : 683 - 732
[8] CALCIUM ENTRY INCREASES THE SENSITIVITY OF CEREBELLAR PURKINJE-CELLS TO APPLIED GABA AND DECREASES INHIBITORY SYNAPTIC CURRENTS
LLANO, I
LERESCHE, N
MARTY, A
[J]. NEURON, 1991, 6 (04) : 565 - 574
[9] Neuroscience - A tale of two transmitters
Nicoll, RA
Malenka, RC
[J]. SCIENCE, 1998, 281 (5375) : 360 - 361
[10] Ralevic V, 1998, PHARMACOL REV, V50, P413

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