Shaping amorphous calcium carbonate films into 2D model substrates for bone cell culture

被引：45

作者：

Popescu, DC

van Leeuwen, ENM

Rossi, NAA

Holder, SJ

Jansen, JA

Sommerdijk, NAJM

机构：

[1] Eindhoven Univ Technol, Lab Macromol & Organ Chem, NL-5600 MB Eindhoven, Netherlands

[2] Univ Kent, Sch Phys Sci, Funct Mat Grp, Canterbury CT2 7NR, Kent, England

[3] Radboud Univ Nijmegen, Nijmegen Med Ctr, Dept Periodontol & Biomat, NL-6500 HB Nijmegen, Netherlands

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 11期

关键词：

biomimetic synthesis; block copolymers; bone cells; photolithography; thin films;

D O I：

10.1002/anie.200502602

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Boning up on patterning: Patterned calcium carbonate films with dimensions of 200-400 μm were obtained using the photolithographic properties of a polysilane-based ABA block copolymer, PHEMA-PMPS-PHEMA. These patterns may serve as a 2D model system for CaCO 3 biomaterials in which both the CaCO3 resorption by osteoclasts and the calcium phosphate deposition by osteoblasts can be monitored using optical microscopy. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

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收藏

页码：1762 / 1767

页数：6

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