Sol-gel based fabrication and characterization of new bioactive glass-ceramic composites for dental applications

被引：47

作者：

Chatzistavrou, Xanthippi ^{[2
]}

Tsigkou, Olga ^{[2
]}

Amin, Harsh D. ^{[3
]}

Paraskevopoulos, Konstantinos M. ^{[4
]}

Salih, Vehid ^{[3
]}

Boccaccini, Aldo R. ^{[1
,2
]}

机构：

[1] Univ Erlangen Nurnberg, Inst Biomat, Dept Mat Sci & Engn, D-91058 Erlangen, Germany

[2] Univ London Imperial Coll Sci Technol & Med, Dept Mat, London SW7 2AZ, England

[3] UCL Eastman Dent Inst, Dept Biomat & Tissue Engn, London WC1X 8LD, England

[4] Aristotle Univ Thessaloniki, Dept Phys, Solid State Sect, Thessaloniki 54124, Greece

来源：

JOURNAL OF THE EUROPEAN CERAMIC SOCIETY | 2012年 / 32卷 / 12期

关键词：

Sol-gel processes; Composites; Glass-ceramics; Biomedical applications; Dental ceramics; PERIODONTAL-LIGAMENT; PROLIFERATION; FIBROBLASTS; RESTORATIONS; TISSUE; UNIQUE; RATES;

D O I：

10.1016/j.jeurceramsoc.2012.04.037

中图分类号：

TQ174 [陶瓷工业]; TB3 [工程材料学];

学科分类号：

081705 [工业催化]; 082905 [生物质能源与材料];

摘要：

The fabrication of a new composite glass-ceramic with potential application in dental restoration was investigated. The developed material aims to modify the surface of dental ceramics creating bioactive surfaces able to improve material-cell interaction enhancing the bonding of the marginal gap between restoration and tooth. The application of the sol-gel method led to a microporous homogeneous glass-ceramic which can be applied as coating on commercial dental ceramic substrates. The rnicrostructural, thermal, mechanical and biological properties of the fabricated coatings were studied and compared to the respective results of a previously investigated glass-ceramic composite. The material-cell interaction on these two sol-gel dental composites was studied in detail. The attachment and proliferation of both periodontal ligament and gingival fibroblast cells confirmed the bioactive behavior of the new materials and their ability to be potentially applied in dental restorations for soft tissue regeneration and sealing of the marginal gap. (c) 2012 Elsevier Ltd. All rights reserved.

引用

页码：3051 / 3061

页数：11

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