The role of M cells in Salmonella infection

被引:124
作者
Jepson, MA [1 ]
Clark, MA
机构
[1] Univ Bristol, Cell Imaging Facil, Bristol BS8 1TD, Avon, England
[2] Univ Bristol, Dept Biochem, Bristol BS8 1TD, Avon, England
[3] Newcastle Univ, Dept Physiol Sci, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
基金
英国惠康基金; 英国医学研究理事会;
关键词
Salmonella; Peyer's patch; follicle-associated epithelium; Salmonella pathogenicity island 1; invasion;
D O I
10.1016/S1286-4579(01)01478-2
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Intestinal M cells, the specialised antigen-sampling cells of the mucosal immune system, are exploited by Salmonella and other pathogens as a route of invasion. Salmonella entry into M cells and colonisation of Peyer's patches involve mechanisms critical for infection of cultured cells as well as factors not accurately modelled in vitro. (C) 2001 Editions scientifiques et medicales Elsevier SAS.
引用
收藏
页码:1183 / 1190
页数:8
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