Chitosan beads with pendant α-cyclodextrin:: preparation and inclusion property to nitrophenolates

被引：35

作者：

Tojima, T ^{[1
]}

Katsura, H

Nishiki, M

Nishi, N

Tokura, S

Sakairi, N

机构：

[1] Hokkaido Univ, Grad Sch Environm Earth Sci, Div Biosci, Sapporo, Hokkaido 0600810, Japan

[2] Kansai Univ, Fac Engn, Osaka 5640073, Japan

来源：

CARBOHYDRATE POLYMERS | 1999年 / 40卷 / 01期

关键词：

cyclodextrin; chitosan; p-nitrophenol; inclusion complex; controlled release;

D O I：

10.1016/S0144-8617(99)00030-2

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Highly porous beads having an ability to form inclusion complexes with specific substrates have been synthesized and preliminary experiments for the application to adsorbent for affinity column chromatography and controlled release were carried out. Water-insoluble chitosan beads were synthesized by adding an aqueous acetic acid solution of chitosan into ethanolic aqueous sodium hydroxide and subsequent crosslinking with hexamethylene diisocyanate in N, N-dimethylformamide. The resulting beads were further treated with 2-O-formylmethyl-alpha-cyclodextrin in the presence of sodium cyanoborohydride in acetate buffer at pH 4.4, giving the cyclodextrin-linked chitosan beads. Their inclusion ability was examined by the use of p-nitrophenol and its analogue as model compounds. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：17 / 22

页数：6

共 17 条

[1]

[Anonymous], CYCLODEXTRIN THEIR I

[2] LIQUID-CHROMATOGRAPHIC SEPARATION OF DIASTEREOMERS AND STRUCTURAL ISOMERS ON CYCLODEXTRIN-BONDED PHASES [J].

ARMSTRONG, DW ;

DEMOND, W ;

ALAK, A ;

HINZE, WL ;

RIEHL, TE ;

BUI, KH .

ANALYTICAL CHEMISTRY, 1985, 57 (01) :234-237

[3] DISPOSITION REQUIREMENTS FOR BINDING IN AQUEOUS-SOLUTION OF POLAR SUBSTRATES IN CYCLOHEXAAMYLOSE CAVITY [J].

BERGERON, RJ ;

CHANNING, MA ;

GIBEILY, GJ ;

PILLOR, DM .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1977, 99 (15) :5146-5151

[4] Facile preparation and inclusion ability of a chitosan derivative bearing carboxymethyl-beta-cyclodextrin [J].

Furusaki, E ;

Ueno, Y ;

Sakairi, N ;

Nishi, N ;

Tokura, S .

CARBOHYDRATE POLYMERS, 1996, 29 (01) :29-34

[5] Metal-anion sorption by chitosan beads: Equilibrium and kinetic studies [J].

Guibal, E ;

Milot, C ;

Tobin, JM .

INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 1998, 37 (04) :1454-1463

[6] THE SYNTHESIS OF FUNCTIONALIZED CYCLODEXTRINS AS SCAFFOLDS AND TEMPLATES FOR MOLECULAR DIVERSITY, CATALYSIS, AND INCLUSION PHENOMENA [J].

HANESSIAN, S ;

BENALIL, A ;

LAFERRIERE, C .

JOURNAL OF ORGANIC CHEMISTRY, 1995, 60 (15) :4786-4797

[7]

HORTON D., 1965, METHOD CARBOHYD CHEM, V5, P403

[8] Continuous hydrolysis of pectate by immobilized endo-polygalacturonase in a continuously stirred tank reactor [J].

Iwasaki, K ;

Inoue, M ;

Matsubara, Y .

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 1998, 62 (02) :262-267

[9] Elution of Hg(II) adsorbed on highly porous polyaminated chitosan beads [J].

Kawamura, Y ;

Yoshida, H ;

Asai, S ;

Tanibe, H .

JOURNAL OF CHEMICAL ENGINEERING OF JAPAN, 1998, 31 (01) :115-118

[10]

Muzzarelli R, 1986, Chitin in nature and technology

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