Mild cleavage of aliphatic epoxides with substituted anilines on alumina

被引：56

作者：

Harrak, Y ^{[1
]}

Pujol, MD ^{[1
]}

机构：

[1] Univ Barcelona 643, Fac Farm, Quim Farmaceut Lab, E-08028 Barcelona, Spain

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 05期

关键词：

1,2-epoxides; aluminum oxide; anilines; ring opening;

D O I：

10.1016/S0040-4039(01)02280-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Aluminum oxide has been used in the ring opening of epoxides by anilines. This ne v heterogeneous reaction competes favourably with the usual reactions and the products obtained are of high purity. The yields of the amino-alcohols are uniformly good and the recovered alumina could be used in a new attempt without alteration. (C) 2002 Published by Elsevier Science Ltd.

引用

页码：819 / 822

页数：4

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