High-performance liquid chromatography of some bases and nucleosides on alkylphosphonate-modified magnesia-zirconia column

被引：21

作者：

Fu, HJ ^{[1
]}

Feng, YQ

Zhang, QH

Da, SL

Zhang, YJ

机构：

[1] Wuhan Univ, Dept Chem, Wuhan 430072, Peoples R China

[2] Cent China Normal Univ, Ctr Anal & Testing, Wuhan 430079, Peoples R China

来源：

ANALYTICAL LETTERS | 1999年 / 32卷 / 14期

关键词：

HPLC; magnesia-zirconia composite; alkyphosphonate modification; bases; nucleosides;

D O I：

10.1080/00032719908543004

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The high-performance liquid chromatographic behavior of some bases and nucleosides was studied on a new reversed-phase stationary phase, alkylphosphonate-modified magnesia-zirconia. The effect of mobile phase variable such as methanol content, ionic strength and pH on their behavior was investigated. It was found that the retention behavior of the bases and nucleosides on the new stationary phase is similar to that on ODS stationary phase. The retention mechanism on the new stationary phase was also discussed. The separation of some bases and nucleosides was accomplished on the new stationary phase.

引用

页码：2761 / 2774

页数：14

共 15 条

[1] STRUCTURE-RETENTION RELATIONS IN THE REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY OF PURINE AND PYRIMIDINE COMPOUNDS [J].