Selective blockade of androgenic steroid synthesis by novel lyase inhibitors as a therapeutic strategy for treating metastatic prostate cancer

被引：164

作者：

Attard, G ^{[1
]}

Belldegrun, AS

de Bono, JS

机构：

[1] Royal Marsden NHS Fdn Trust, Inst Canc Res, Ctr Canc Therapeut, Surrey, England

[2] Univ Calif Los Angeles, David Geffen Sch Med, Dept Urol, Los Angeles, CA USA

来源：

BJU INTERNATIONAL | 2005年 / 96卷 / 09期

关键词：

castration refractory prostate cancer; 17; alpha-hydroxylase; C-17; C-20-lyase; CYP450c17; abiraterone; CB7630;

D O I：

10.1111/j.1464-410X.2005.05821.x

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：1241 / 1246

页数：6

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