Evidence for an insertion-homolysis mechanism for carbon-sulphur bond formation in penicillin biosynthesis .1. Synthesis of tripeptide probes

被引：17

作者：

Baldwin, JE ^{[1
]}

Adlington, RM ^{[1
]}

Marquess, DG ^{[1
]}

Pitt, AR ^{[1
]}

Porter, MJ ^{[1
]}

Russell, AT ^{[1
]}

机构：

[1] OXFORD CTR MOLEC SCI,OXFORD OX1 3QY,ENGLAND

来源：

TETRAHEDRON | 1996年 / 52卷 / 07期

关键词：

D O I：

10.1016/0040-4020(95)01071-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Synthesis of four LLD-ACV analogues, in which the valine residue has been replaced by an amino acid containing a stereospecifically deuterated cyclopropane ring, is described.

引用

页码：2515 / 2536

页数：22

共 34 条

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BALDWIN, JE
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[7] STEREOSPECIFICITY OF CARBON-SULFUR BOND FORMATION IN PENICILLIN BIOSYNTHESIS
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[J]. JOURNAL OF HETEROCYCLIC CHEMISTRY, 1990, 27 (01) : 71 - 78
[9] Black T.H., 1983, ALDRICHIM ACTA, V16, P3
[10] Bodanszky M., 1984, PRACTICE PEPTIDE SYN, p[20, 170]

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