Screening, Assessment, and Management of Fatigue in Adult Survivors of Cancer: An American Society of Clinical Oncology Clinical Practice Guideline Adaptation

被引：442

作者：

Bower, Julienne E. ^{[1
]}

Bak, Kate ^{[2
]}

Berger, Ann ^{[3
]}

Breitbart, William ^{[4
]}

Escalante, Carmelita P. ^{[5
]}

Ganz, Patricia A. ^{[1
]}

Schnipper, Hester Hill ^{[6
]}

Lacchetti, Christina ^{[2
]}

Ligibel, Jennifer A. ^{[7
]}

Lyman, Gary H. ^{[9
,10
]}

Ogaily, Mohammed S. ^{[11
]}

Pirl, William F. ^{[8
]}

Jacobsen, Paul B. ^{[12
]}

机构：

[1] Univ Calif Los Angeles, Los Angeles, CA USA

[2] Amer Soc Clin Oncol, Alexandria, VA 22314 USA

[3] NIH, Ctr Clin, Bethesda, MD 20892 USA

[4] Mem Sloan Kettering Canc Ctr, New York, NY 10021 USA

[5] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA

[6] Beth Israel Deaconess Med Ctr, Boston, MA USA

[7] Dana Farber Canc Inst, Boston, MA USA

[8] Massachusetts Gen Hosp, Boston, MA 02114 USA

[9] Fred Hutchinson Canc Res Ctr, Seattle, WA 98104 USA

[10] Univ Washington, Seattle, WA 98195 USA

[11] Oakwood Ctr Hematol & Oncol, Brownstown, MI USA

[12] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL USA

来源：

JOURNAL OF CLINICAL ONCOLOGY | 2014年 / 32卷 / 17期

关键词：

QUALITY-OF-LIFE; BREAST-CANCER; PHYSICAL-ACTIVITY; EXERCISE; THERAPY; INTERVENTIONS; MEDICINE; IMPACT; MOOD; COMPLEMENTARY;

D O I：

10.1200/JCO.2013.53.4495

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Purpose This guideline presents screening, assessment, and treatment approaches for the management of adult cancer survivors who are experiencing symptoms of fatigue after completion of primary treatment. Methods A systematic search of clinical practice guideline databases, guideline developer Web sites, and published health literature identified the pan-Canadian guideline on screening, assessment, and care of cancer-related fatigue in adults with cancer, the National Comprehensive Cancer Network (NCCN) Clinical Practice Guidelines In Oncology (NCCN Guidelines) for Cancer-Related Fatigue and the NCCN Guidelines for Survivorship. These three guidelines were appraised and selected for adaptation. Results It is recommended that all patients with cancer be evaluated for the presence of fatigue after completion of primary treatment and be offered specific information and strategies for fatigue management. For those who report moderate to severe fatigue, comprehensive assessment should be conducted, and medical and treatable contributing factors should be addressed. In terms of treatment strategies, evidence indicates that physical activity interventions, psychosocial interventions, and mind-body interventions may reduce cancer-related fatigue in post-treatment patients. There is limited evidence for use of psychostimulants in the management of fatigue in patients who are disease free after active treatment. Conclusion Fatigue is prevalent in cancer survivors and often causes significant disruption in functioning and quality of life. Regular screening, assessment, and education and appropriate treatment of fatigue are important in managing this distressing symptom. Given the multiple factors contributing to post-treatment fatigue, interventions should be tailored to each patient's specific needs. In particular, a number of nonpharmacologic treatment approaches have demonstrated efficacy in cancer survivors.

引用

页码：1840 / U127

页数：12

共 64 条

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