Autoimmune thrombocytopenia in a patient with small cell lung cancer developing after chemotherapy and resolving following autologous peripheral blood stem cell transplantation

被引：40

作者：

Demirer, T ^{[1
]}

Çelebi, H

Arat, M

Üstün, C

Demirer, S

Dilek, I

Özcan, M

Ilhan, O

Akan, H

Gürman, G

Koç, H

机构：

[1] Ankara Univ, Sch Med, Ibn I Sina Hosp, Dept Hematol Oncol, TR-06100 Ankara, Turkey

[2] Ankara Univ, Sch Med, Ibn I Sina Hosp, Bone Marrow Transplant Unit, TR-06100 Ankara, Turkey

[3] Ankara Univ, Sch Med, Ibn I Sina Hosp, Dept Surg, TR-06100 Ankara, Turkey

来源：

BONE MARROW TRANSPLANTATION | 1999年 / 24卷 / 03期

关键词：

autoimmune thrombocytopenia; small cell lung cancer; autologous peripheral blood stem cell transplantation;

D O I：

10.1038/sj.bmt.1701902

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

A 46-year-old white male with small cell lung cancer (SCLC) limited to the thorax developed autoimmune thrombocytopenic purpura (AITP), following a cyclophosphamide, paclitaxel and G-CSF-containing regimen for peripheral blood stem cell (PBSC) mobilization. AITP associated with small or non-small cell lung cancer has been reported. We considered that the AITP in this case may be a part of paraneoplastic syndrome, which is frequently seen in patients with SCLC. The patient received HDC and autologous PBSC transplantation (APBSCT) for SCLC and the AITP resolved following transplantation, thus supporting the concept of HDC + APBSCT for the treatment of autoimmune diseases.

引用

页码：335 / 337

页数：3

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