Outcomes of endovascular interventions for TASC II B and C femoropopliteal lesions

被引:55
作者
Baril, Donald T. [1 ]
Marone, Luke K. [1 ]
Kim, Justine [1 ]
Go, Michael R. [1 ]
Chaer, Rabih A. [1 ]
Rhee, Robert Y. [1 ]
机构
[1] Univ Pittsburgh, Med Ctr, Div Vasc Surg, Dept Surg, Pittsburgh, PA USA
关键词
D O I
10.1016/j.jvs.2008.04.059
中图分类号
R61 [外科手术学];
学科分类号
摘要
Objective: To evaluate outcomes of endovascular interventions on femoropopliteal occlusive disease and determine predictors of restenosis of Trans Atlantic Inter-Societal Consensus (TASC) 11 B and C lesions. Methods: All patients undergoing endovascular interventions for femoropopliteal occlusive disease between May 2003 and July 2007 were reviewed. Patient demographics, pre- and post-procedure ankle-brachial indices (ABI), and anatomic factors (including categorization by TASC 11 classification, lesion length, and runoff vessel status) were analyzed. Outcomes evaluated included freedom from restenoses, freedom from re-intervention, overall patency, and assisted-patency. Results: A total of 237 total limbs were treated during the period reviewed. The study group included 108 TASC B and 32 TASC C limbs in 125 patients (mean age 73.1 +/- 10.4 years, male sex: 59%). Seventy-one percent of patients were Rutherford classification 2/3 while the remaining 29% were Rutherford classification 4/5. Mean follow-tip period was 12.7 months (range, 1-52 in). Forty-one (41) limbs experienced restenosis or occlusion at a mean time of 8 months (range, 1-24 in). Freedom front restenosis/occlusion was 58.9% at 12 months and 47.9% at 24 months. Predictors of restenosis included a preoperative ABI < 0.5 (hazard ratio [HR] 3.05, 95% confidence interval [CI] 1.36-6.86, P = .007) and hypercholesterolemia (HR 2.42, 95% Cl 1.11-5.25, P = .025). Lesion length as a Continuous variable (per centimeter) also correlated with a higher risk of restenosis (HR 1.06, 95% CI 1.00-1.12, P = .057). The overall assisted-primary and secondary-patency rates were 87% and 94% respectively at 3 years with no significant differences between TASC B and TASC C limbs. Conclusion: Endovascular interventions for TASC I I B and C lesions are associated with restenosis/occlusion rates that are at least as good as those of open femoropopliteal bypass surgery from historical, previously published series. Furthermore, overall assisted-patency rates are excellent, although low preoperative ABIs continue to be associated with worse outcomes.
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页码:627 / 633
页数:7
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