No-D NMR (No-Deuterium proton NMR) spectroscopy: A simple yet powerful method for analyzing reaction and reagent solutions

被引：106

作者：

Hoye, TR ^{[1
]}

Eklov, BM ^{[1
]}

Ryba, TD ^{[1
]}

Voloshin, M ^{[1
]}

Yao, LJ ^{[1
]}

机构：

[1] Univ Minnesota, Dept Chem, Minneapolis, MN 55455 USA

来源：

ORGANIC LETTERS | 2004年 / 6卷 / 06期

关键词：

D O I：

10.1021/ol049979+

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The title technique is a convenient and powerful method for directly monitoring or assaying any reaction mixture or reagent solution. Examples of some common processes (Fischer esterification, lithiation, butyllithium/THF compatibility, olefin metathesis, and a quantification assay), each interrogated in its native solvent, are presented. The spectral data are easy to acquire, and the information content makes a compelling case for routine use of No-D NMR spectroscopy.

引用

页码：953 / 956

页数：4

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