Candida africana sp nov., a new human pathogen or a variant of Candida albicans?

被引：70

作者：

Tietz, HJ

Hopp, M

Schmalreck, A

Sterry, W

Czaika, V

机构：

[1] Humboldt Univ, Fak Med, Klin Dermatol Venerol & Allergol, D-1040 Berlin, Germany

[2] Humboldt Univ, Fak Med, Univ Klinikum Charite, Zentrum Zahnmed, D-1040 Berlin, Germany

[3] Heinrich Mack Nachf, Abt Mikrobiol, Illertissen, Germany

[4] Humaine Klinikum, Innere Med Klin, Bad Saarow Pieskow, Germany

来源：

MYCOSES | 2001年 / 44卷 / 11-12期

关键词：

Candida africana sp nov; taxonomy; systematics; epidemiology;

D O I：

10.1046/j.1439-0507.2001.00707.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Atypical Candida strains were isolated from patients in Madagascar, Angola and Germany. These isolates were slow growing and were unable to produce chlamydospores. They had atypical carbohydrate assimilation profiles. All strains were unable to assimilate the amino sugars N-acteylglucosamine and glucosamine as well as the disaccharide trehalose and the organic acid DL-lactate. They were germ-tube-positive in serum, but only some of these organisms produced pseudohyphae after a long incubation. As shown by Fourier transform infrared spectroscopy the atypical Candida isolates clustered as a monophyletic group different from C. albicans and C. dubliniensis. All strains belonged to C. albicans serotype B. Considering all data presented here, this group of Candida strains differs from an), other known member of the genus Candida. Therefore, it is suggested to represent a new species within the genus Candida for which the name Candida africana is proposed.

引用

页码：437 / 445

页数：9

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