Human-porcine receptor-ligand compatibility within the immune system: relevance for xenotransplantation

被引：31

作者：

Warrens, AN ^{[1
]}

Simon, AR ^{[1
]}

Theodore, PR ^{[1
]}

Sykes, M ^{[1
]}

机构：

[1] Harvard Univ, Massachusetts Gen Hosp, Sch Med,Transplantat Biol Res Ctr, Bone Marrow Transplantat Sect, Boston, MA 02129 USA

来源：

XENOTRANSPLANTATION | 1999年 / 6卷 / 02期

关键词：

adhesion molecules; co-stimulation transplantation; selectins; integrins; major histocompatibility complex; tolerance; xenotransplantation;

D O I：

10.1034/j.1399-3089.1999.00020.x

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Immune responses to xenografts are likely to be highly dependent on the efficiency of molecular interactions between the donor and the recipient species. This brief review summarizes what is currently known about the compatibilities across the human-porcine species barrier of the molecular interactions that are important in the immune response.

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页码：75 / 78

页数：4

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