Hispidin analogs from the mushroom Inonotus xeranticus and their free radical scavenging activity

被引：87

作者：

Lee, IK ^{[1
]}

Yun, BS ^{[1
]}

机构：

[1] Korea Res Inst Biosci & Biotechnol, Taejon 305333, South Korea

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2006年 / 16卷 / 09期

关键词：

antioxidant; free radical scavenger; mushroom; Inonotus xeranticus; hispidin analog;

D O I：

10.1016/j.bmcl.2006.01.121

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Three new free radical scavengers were isolated from the methanolic extract of the fruiting bodies of Inonotus xeranticus (Hymenochaetaceae), along with the known compound davallialactone. Their structures were established as hispidin analogs by extensive NMR spectral data. Compounds 3 and 4 displayed significant scavenging activity against the superoxide radical anion, ABTS radical cation, and DPPH radical, while 1 and 2 exhibited potent antioxidative activity only against ABTS radical cation. (C) 2006 Elsevier Ltd. All rights reserved.

引用

页码：2376 / 2379

页数：4

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