Dominant lethality and insect population control

被引:97
作者
Alphey, L [1 ]
Andreasen, M [1 ]
机构
[1] Univ Oxford, Dept Zool, Oxford OX1 3PS, England
关键词
dominant lethality; genetic engineering; insect population control;
D O I
10.1016/S0166-6851(02)00040-3
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Recent advances in insect genetic engineering have opened up new possibilities in the genetic control of insect vectors of human diseases. We outline the current state of the sterile insect technique and show how the use of engineered dominant lethals can greatly increase the effectiveness of this approach. We consider alternative strategies based on the use of conditional dominant lethals that are not always active in the environment. (C) 2002 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:173 / 178
页数:6
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