The drug delivery system of MCM-41 materials via co-condensation synthesis

被引：66

作者：

Zeng, W

Qian, XF ^{[1
]}

Yin, J

Zhu, ZK

机构：

[1] Shanghai Jiao Tong Univ, Sch Chem & Chem Technol, State Key Lab Composite Mat, Shanghai 200240, Peoples R China

[2] Tianjin Univ Sci & Technol, Coll Mat Sci & Chem Engn, Tianjin 300222, Peoples R China

来源：

MATERIALS CHEMISTRY AND PHYSICS | 2006年 / 97卷 / 2-3期

基金：

中国国家自然科学基金;

关键词：

co-condensation; MCM-41; drug delivery;

D O I：

10.1016/j.matchemphys.2005.08.040

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

The functional MCM-41 materials were prepared through co-condensation method, as compared postsynthesis and solvothermal processes were also used. The as-functionalized MCM-41 materials have been characterized by XRD, TEM, N-2 adsorption and Si-29 CP/MAS NMR. The modified materials have been used as drug-controlled delivery system of aspirin. The results showed that the release properties of this system were affected by functionalization degree and the distribution of functional groups on the pore wall surface of mesoporous materials, and the better delivery rate of MCM-41 materials would be obtained via co-condensation process. (c) 2005 Elsevier B.V. All fights reserved.

引用

页码：437 / 441

页数：5

共 15 条

[1] Pyrene covalently anchored on a large external surface area zeolite as a selective heterogeneous sensor for iodide [J].

Corma, A ;

Galletero, MS ;

García, H ;

Palomares, E ;

Rey, F .

CHEMICAL COMMUNICATIONS, 2002, (10) :1100-1101

[2] From microporous to mesoporous molecular sieve materials and their use in catalysis [J].

Corma, A .

CHEMICAL REVIEWS, 1997, 97 (06) :2373-2419

[3]

Ganschow M, 2000, ANGEW CHEM INT EDIT, V39, P161

[4] Organic functionalization and morphology control of mesoporous silicas via a co-condensation synthesis method [J].

Huh, S ;

Wiench, JW ;

Yoo, JC ;

Pruski, M ;

Lin, VSY .

CHEMISTRY OF MATERIALS, 2003, 15 (22) :4247-4256

[5]

JARONIEC M, 2003, MESOPOROUS MOL SIEVE, V17, P325

[6] A mesoporous silica nanosphere-based carrier system with chemically removable CdS nanoparticle caps for stimuli-responsive controlled release of neurotransmitters and drug molecules [J].

Lai, CY ;

Trewyn, BG ;

Jeftinija, DM ;

Jeftinija, K ;

Xu, S ;

Jeftinija, S ;

Lin, VSY .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (15) :4451-4459

[7] SI-29 NUCLEAR MAGNETIC-RESONANCE STUDY OF THE SURFACE OF SILICA-GEL BY CROSS POLARIZATION AND MAGIC-ANGLE SPINNING [J].

MACIEL, GE ;

SINDORF, DW .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1980, 102 (25) :7606-7607

[8] Photo-switched storage and release of guest molecules in the pore void of coumarin-modified MCM-41 [J].

Mal, NK ;

Fujiwara, M ;

Tanaka, Y ;

Taguchi, T ;

Matsukata, M .

CHEMISTRY OF MATERIALS, 2003, 15 (17) :3385-3394

[9] Photocontrolled reversible release of guest molecules from coumarin-modified mesoporous silica [J].

Mal, NK ;

Fujiwara, M ;

Tanaka, Y .

NATURE, 2003, 421 (6921) :350-353

[10] HETEROGENEOUS CATALYSTS OBTAINED BY GRAFTING METALLOCENE COMPLEXES ONTO MESOPOROUS SILICA [J].

MASCHMEYER, T ;

REY, F ;

SANKAR, G ;

THOMAS, JM .

NATURE, 1995, 378 (6553) :159-162

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